Medically reviewed by Dr. Victor Gura, Nephrology Specialist 
Moderate kidney dysfunction, classified as Stage 3 chronic kidney disease (CKD), means your kidneys are filtering at about 30–59% of normal function. It often progresses from mild dysfunction if not managed properly. While symptoms may still be subtle, moderate dysfunction needs active medical attention to avoid serious complications.
📈 What Does Moderate Kidney Dysfunction Mean?
It’s usually diagnosed when your estimated glomerular filtration rate (eGFR) is between 30 to 59 mL/min/1.73m². This indicates your kidneys are filtering less waste from your blood than they should, which can lead to a buildup of toxins.
🔍 Key Symptoms of Moderate Kidney Dysfunction
- Persistent fatigue and low energy
- Swelling in ankles, feet, or hands
- Muscle cramps
- Changes in urination (amount, frequency, or color)
- Sleep disturbances
- Metallic taste or bad breath (uremic breath)
⚠️ Common Causes
- Long-term diabetes or hypertension
- Autoimmune diseases like lupus
- Polycystic kidney disease
- Frequent use of nephrotoxic medications
- Recurrent kidney infections or obstructions
📊 Diagnostic Tests
- Serum creatinine and BUN
- eGFR (estimated Glomerular Filtration Rate)
- Urine protein-to-creatinine ratio
- Renal ultrasound for structural issues
Use our free CrCl Calculator to estimate your creatinine clearance and monitor kidney health at home.
🛡️ Treatment & Management Tips
- Follow a kidney-friendly diet (low sodium, low phosphorus, moderate protein)
- Control blood pressure (below 130/80 mmHg)
- Manage blood sugar levels if diabetic
- Stop smoking and limit alcohol
- Take medications exactly as prescribed
- Regular monitoring with a nephrologist
🏥 When to Seek Medical Help
If you experience rapid weight gain, confusion, nausea, or chest pain, contact your healthcare provider immediately. These can be signs of worsening kidney failure.